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CRISPR Prime - The world’s first biological surgical tool to repair genetic diseases . What was known: For the first time, the method known as “CRISPR” has given us a cheap, easy and effective way edit DNA. This lets researchers easily pick a gene we want to study, destroy it, and study the effects. This type of experiment has allowed us to learn more about our bodies, our genome, and how they work together. The goal for the future is to use this technology to fix instead of destroy the gene we choose. There are more than 6000 genetic diseases, and currently less than 5% have effective treatments, and most treatments simply mask the symptoms of the disease and do not offer a cure. CRISPR may offer that cure. . What they found: The biggest factor holding CRISPR back from being implemented in medicine is that along with editing the intended site, it edits a lot of DNA we do not want changed (which can be very bad). This newest CRISPR system, called CRISPR Prime, uses the best parts of CRISPR but with added safety checks to limit the number of unwanted DNA edits.  They have also created an effective tool that can not only destroy a target gene, but can fix genes as well. . Why it’s cool: CRISPR Prime is the first technology that has ever been created that has the potential to fix the broken parts of genes that cause genetic diseases. In the next few years many researchers around the world will be testing every aspect of the technology to ensure that it is both safe and effective for future patients. CRISPR Prime might thus be used someday to treat or cure many genetic diseases. . . Anzalone et al. 2019 DOI:10.1038/s41586-019-1711-4 . . Written by @tiffany.carlaw . Follow @layscience for more! #layscience #science #learnscience #learn #CRISPR #DNA #genetics #genome #geneedit #prime #crisprprime #guide #cut #disease #geneticdisorder

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O cantor GABIEL MUSSE foi o convidado especial do programa OS VACILÕES DA NOITE da última sexta, 06/12, ao vivo, nos estúdios da Giros LIVE TV! Confira!!! #osvaciloesdanoite @gabrielmusse @giroslivetv @carlosmessiba #sertanejouniversitário #arrochanejo #musicaromantica #dna

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ab.initio.genealogy. I is for Isle of Man 🇮🇲 Grandad John Cowell born 1898 in Douglas Isl

I is for Isle of Man 🇮🇲 Grandad John Cowell born 1898 in Douglas Isle of Man. This is him visiting his sisters in the IOM Lilian 1901 and Ivy 1897. #genealogyphotoaday #isleofman #douglas #cowell #haberdashery #burbridge #Ancestryuk #ancestrydna #Genealogy #Familytree #researcher #family #grandparents #history #greataunt #cowell #familysearch #victorian #victorianphotography #generations #genealogywork #dna #oldphotos #vintagephotography #greatgrandad

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lindahardy_news_fan. | JE T’AI DIT NON GARANCE 😤|
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Clémentine : « ça va ma chérie ? »
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G

| JE T’AI DIT NON GARANCE 😤| • Clémentine : « ça va ma chérie ? » - Garance : « très bien, j’voulais t’dire heu ... avec papa vous allez pouvoir être tranquille un peu ! » - Clémentine : « comment ça ? » - Garance : « j’vais vivre chez Maxime ! Vous allez pouvoir jouer au jeune couple. » - Clémentine : « pardon ? » - Garance : « non mais ça va, c’est juste le temps que des parents soient en voyage de noces. » - Clémentine : « heu bah ... mais même, on s’installe pas chez les gens comme ça ! » - Garance : « ouais, mais j’risque pas d’les déranger puisque y sont pas là ... » - Clémentine : « de toute façon moi j’refuse ! » - Garance : « mais depuis quand j’ai pas l’droit de dormir chez mon mec ? » - Clémentine : « mais enfin, on parle pas d’une nuit pendant l’week-end là ! Il est hors de question que tu t’la cool douce pendant les semaines de cours ! » - Garance : « mais c’est n’importe quoi ! J’ferai mes devoirs, j’réviserai pis j’serai à l’heure en cours. » - Clémentine : « bah oui bien sûr ... tu seras exemplaire, alors que tu seras avec Maxime sans adulte autour ... » - Garance : « putain, mais c’est quoi ton problème ? T’es vraiment relou depuis qu’on est à Sète hein ! » - Clémentine : « hey, tu me parles autrement s’il te plaît hein ! » - Garance : « mais c’est toi qui vrille à chaque fois que j’te parle de Maxime ... qu’est-ce que t’as contre lui ? » - Clémentine : « j’ai rien contre Maxime, tu le verra ici au lycée ! c’est clair ? » - Garance : « non, mais j’crois que t’a vraiment oublier c’que c’était d’être amoureuse hein, et d’avoir besoin d’être ensemble tout l’temps ! » • @lindahardy_officiel @esther_valding @dna_tf1 #DemainNousAppatient #DNA #Série #Épisode302 #TF1 #FlashBack #Lycée #PaulValéry #Discussion #MèreEtFille #Imcompréhension #Crise #Love #Amour #Histoire #LoveStory #Clemax #LindaHardy #EstherValding

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galeri_alqolam_ihsan_rizmi. *Open Arisan Little Abid*

Program Little Abid hadir untuk mengoptimal

*Open Arisan Little Abid* Program Little Abid hadir untuk mengoptimalkan kecerdasan buah hati kita, karena di dalam Little Abid terdiri dari 7 aspek pendidikan yang dapat kita sampaikan ke anak-anak kita. Ke 7 aspek itu meliputi keimanan, moral fisik, akal,social seksual dan kejiwaan. Selain itu, ada 9 Multiple Intelegences dan 4 topik penting seperti Basic Knowledge, Life Skills, General Values, dan Spiritual values. Masih bisa tebus murah Smart Ressa Rp.1.000.000,- atau mau Hafiz Junior gratis untuk pembelian Little Abid cash 😍 (kuota terbatas) #littleabid #bukuanak #bukumasakini #arisanbuku #arisan #openarisan #arisanlittleabid #cordoba #tigaraksa #DnA

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tamadhor14066. #مجسم_dna#DNA#اعمالي#اعمال_مدرسيه
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raraquely. Meet my 3rd bio sister finally! #ancestrydna #dna #biologicalsisters #

Meet my 3rd bio sister finally! #ancestrydna #dna #biologicalsisters #3sacharm #gorgeoussisters #firsttimemeeting

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wismecusa. The unique diamond detail on the PREVA. A great look to a simple mod.⁠

The unique diamond detail on the PREVA. A great look to a simple mod.⁠ ⁠ Preorder the PREVA today and get 10% off!⁠ -⁠⠀⠀⠀⠀⠀⠀⠀⠀⠀⁠ -⁠⠀⠀⠀⠀⠀⠀⠀⠀⠀⁠ -⁠⠀⠀⠀⠀⠀⠀⠀⠀⠀⁠ -⠀⠀⠀⠀⠀⠀⠀⠀⠀⁠ -⁠⠀⠀⠀⠀⠀⠀⠀⠀⠀⁠ #wismec #wismecusa #evolv #prevadna #dna #dnagochop #vapelife #vapelyfe #ejuice #vapeporn #vapecommunity #eliquid #vapefam #instavape #vapedaily #vapeon #vapestagram #vaping #vapenation #vapor #vape #vapehooligans #dripclub #handcheck #vapelove #coilporn

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We are all inherently energy readers. There are many distractions in the 3D but focusing our awareness on where we are leaking energy to people we can then shift away from that dynamic into equality aka matcher energy. This is empowering for all people concerned. If we continue to invest in off-balance and unhealthy dynamics it will then leave us in resentment and suffering which is a choice because we are giving our power away to the other. It’s okay to tell people how you really feel about their behavior, Also more importantly, what is it reflecting back to you about yours. No judgement just awareness. If you are being taken for granted or taken advantage of, speak up with love from a place of integrity. If the other person/s refuse to respect you and don’t appreciate your efforts-boundaries then it’s time to make the choice to honor what you’d truly like to experience in your relationships with family,friends,love partners, coworkers, bosses, virtually anyone you spend time with. You matter. Pay attention to the energy exchange dynamics you are experiencing with your various connections you choose to share your energy with. Remember energy is currency. How are you investing? Read theirs and your own energy and make adjustments accordingly. Taker Energy~They do-invest as little energy as possible and are self oriented, on the path of service to self. Givers~Naturally love to share as much energy as possible with others and do things without being asked. On the path of service to others. New Earth Matchers~ Believe in sharing energy in an equality mindset and don’t take too much or over give. It’s a delicate balance for some especially those who tend to resonate in giver energy. This post is not to shame or blame, it is to rise in awareness at whatever energy you honestly are resonating in. You are the power in your life. Choose wisely and from a place of personal integrity. Honor your inner code like it’s the only thing you have and it will expand into the greatest personal happiness you’ve ever known! #behonest 🌿 Growth will happen! Forgive yourselves and rise in love 💗 This now moment is all that we have. Make it amazing! 👉🏼 @itsaboutdivinetime

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raraquely. Two of my gorgeous sisters ❤️ #sisters #ancestrydna #biologicalsisters

Two of my gorgeous sisters ❤️ #sisters #ancestrydna #biologicalsisters #foundsisters #dna #sistasbythesamemista

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fernandagussen. Misture-se com pessoas de bom coração!

Irmã que a vida me deu! Amo!!!

Misture-se com pessoas de bom coração! Irmã que a vida me deu! Amo!!! 💕💕💕 #irmãs #familiaqueescolhi #teamfabisuperpoderosa #saúde #fitness #esmagaquecresce #estilodevida #bemestar #dna #dnaexperience #amizade #amizadeverdadeira #migasualoka #gratidão

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Some serious team deliberation going on here...serious business judging the nativity scenes. . . . . . . #dnaleadershiptraining #dnateam #dna #leadershiptraining #leadership #photography #training #travel #joy #development #discipleship #gapyear #adventure #freedom #fun #mayhem

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srjbiotechs. Summary : In a new survey of the sub-seafloor off the U.S. Northeast c

Summary : In a new survey of the sub-seafloor off the U.S. Northeast coast, scientists have made a surprising discovery: a gigantic aquifer of relatively fresh water trapped in porous sediments lying below the salty #ocean. It appears to be the largest such formation yet found in the world. The #aquifer stretches from the shore at least from #Massachusetts to New Jersey, extending more or less continuously out about 50 miles to the edge of the continental shelf. . . . . Actually scientists wanted to study the behaviour of electromagnetic #radiation in the ocean . . . . For this purpose the researchers dropped instruments to the seafloor to measure the #electromagnetic fields below. In addition, a tool towed behind the ship emitted #artificial electromagnetic pulses and measured the reactions from the subseafloor . . . . The two methods rely on a similar science: #Salt water conducts electromagnetic waves better than fresh water does . . . . So during their survey all of sudden they started to get a very low signal due to less conductance in the sea water . . . . This phenomenon opened the door to this new discovery because less conductance was an indication towards the fresh water source beneath the sea . . . . Because fresh water contains very negligible amount of electrolyte dissolved in it as compared to sea water, that's why fresh water was giving weak signals. . . . . Source: Earth Institute at Columbia University . . Date : June 2019 . . . #biology #science  #sea #seawater #goodnews #discovery #research #srjbiotechs #biotechnology #chemistry  #water #news #recent4recent #biochemistry #microbiology #osmosis #new #genetics #gene #dna #crispr #pollution #waterpollution

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tymetalheadjohnson. DNA TEST - 23 and Me 😂😂😂 haha  #DNA #fyp #foryoupage #lol #south #f

DNA TEST - 23 and Me 😂😂😂 haha #DNA #fyp #foryoupage #lol #south #fypage #foryou #cousins #23andme

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crispr.daily. In a study published this month in Nature Communications, Japanese res

In a study published this month in Nature Communications, Japanese researchers led by Osaka University describe a new genome editing approach that brings us much closer to achieving the dream of eliminating a host of diseases caused by faults in our DNA. • There are two main classes of CRISPR systems, Class 1 and Class 2, that are distinguished by the number of helper proteins needed to cut the DNA. While most gene editing approaches use single-component Class 2 CRISPR systems, very little is known about the utility of multi-component Class 1 systems in eukaryotic gene editing. • "Class 2 CRISPR systems, particularly those using the Cas9 or Cas12a enzymes, are widely used for eukaryotic genome editing," says lead author of the study Hiroyuki Morisaka. "However, these systems aren't perfect: as well as introducing unintended mutations, genome editing efficiencies using these methods can be somewhat variable." • The researchers therefore decided to investigate whether Class 1 CRISPR systems could offer a more efficient and safer alternative. • Using a Cas3 protein-based Class 1 CRISPR system, the team successfully demonstrated both DNA deletions and insertions in human cells. Notably, the Cas3 protein-induced unidirectional deletions of large sections of DNA, setting it apart from Class 2 enzymes which usually need help to achieve such large genome edits. Most importantly though, Cas3 achieved more efficient genome editing than Cas9, with no prominent off-target effects. • To confirm the therapeutic potential of the system, the researchers carried out Cas3-based repair of the DMD gene in induced pluripotent stem cells from a patient with Duchenne muscular dystrophy. • "Our results suggest that this Cas3-based method offers a superior alternative to Class 2 CRISPR gene editing systems," says senior author Tomoji Mashimo. "As well as its obvious therapeutic uses, we envisage potential applications in drug discovery, disease prevention, and crop improvement." [credit: Osaka University, ResOU]🌐

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twowheeljesus. One of the best battles of all time! The homie @iamaward went off... O

One of the best battles of all time! The homie @iamaward went off... On God #GodsPlan #battle #rap #Rideordie #hiphop #rap #dna #award

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So I got my Ancestry DNA result back early and.... I'm not 100% Puerto Rican!! 😭😭 But it's cool to see where my bloodline is from, now I can search for more family members. I found 2 of my lost sisters and a brother, hope I can find the rest. 😊💜

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geneticprotocol. Save on our #neurotransmitterprotocol package. Everything you need to

Save on our #neurotransmitterprotocol package. Everything you need to get started. #depression #anxiety #add #mthfr #methylation #nutrigenomics #DNA #MTHFR www.geneticprotocol.store

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